Efficacy of neem (Azadirachta indica) aqueous fruit extracts against Sarcoptes scabiei var. suis in grower pigs

Abstract

The acaricidal activity of Azadirachta indica (neem) aqueous fruit extracts was evaluated against Sarcoptes scabiei var. suis (mange mites) in an on-farm trial using grower pigs. Aqueous neem fruit extracts of three concentrations 5%, 10%, and 25% w/v and a commercial acaricide, 12.5% amitraz-based Triatix spray (positive control), were compared with pigs that received no treatment (negative control). Thirty grower pigs of the Dalland breed were allocated to the five treatments in a completely randomized experiment. Each experimental animal was sprayed on day 0 and again on day 7. Counts of mange mites, scoring of lesion index, and calculation of rubbing index were done weekly. Topical application of 25% aqueous neem fruit extract had a higher efficacy ratio (p < 0.05) than the other fruit extract concentrations, and performed similarly to an amitraz-based acaricide, suggesting a dose-dependent response. Amitraz (positive control) cured clinical mange on grower pigs after 5 weeks and 25% aqueous neem fruit extract 6 weeks post-treatment. The results indicated that aqueous neem fruit extracts have acaricidal effects against mange mites and can provide a cheaper, safer, and more eco-friendly alternative for the control of Sarcoptes mange in pigs.